发明公开
- 专利标题: ORAL OSMOTIC DOSAGE FORM HAVING A HIGH FLUX MEMBRANE
- 专利标题(中): 用芦苇高密度流动口服渗透药物剂型
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申请号: EP06734068.7申请日: 2006-01-27
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公开(公告)号: EP1858492A2公开(公告)日: 2007-11-28
- 发明人: EDGREN, David, E. , BHATTI, Gurdish, K. , LI, Shu , SKLUZACEK, Robert
- 申请人: Alza Corporation
- 申请人地址: 1900 Charleston Road, M.S. M10-3B Mountain View, CA 94043 US
- 专利权人: Alza Corporation
- 当前专利权人: Alza Corporation
- 当前专利权人地址: 1900 Charleston Road, M.S. M10-3B Mountain View, CA 94043 US
- 代理机构: Williams, Paul Edwin
- 优先权: US647864P 20050127
- 国际公布: WO2006081569 20060803
- 主分类号: A61K9/28
- IPC分类号: A61K9/28
摘要:
Disclosed are oral osmotic dosage forms and methods wherein a semipermeable membrane of the oral osmotic dosage form includes from about 23 wt% to about 50 wt% of a flux enhancer and from about 0.01 wt% to about 5 wt% of antioxidant, based on the total dry weight of the semi-permeable membrane. Such compositions provide high flux membranes with improved mechanical and transport stability during storage on the shelf.
公开/授权文献
- EP1858492B1 ORAL OSMOTIC DOSAGE FORM HAVING A HIGH FLUX MEMBRANE 公开/授权日:2008-11-12
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