发明公开
EP1858492A2 ORAL OSMOTIC DOSAGE FORM HAVING A HIGH FLUX MEMBRANE 有权
用芦苇高密度流动口服渗透药物剂型

  • 专利标题: ORAL OSMOTIC DOSAGE FORM HAVING A HIGH FLUX MEMBRANE
  • 专利标题(中): 用芦苇高密度流动口服渗透药物剂型
  • 申请号: EP06734068.7
    申请日: 2006-01-27
  • 公开(公告)号: EP1858492A2
    公开(公告)日: 2007-11-28
  • 发明人: EDGREN, David, E.BHATTI, Gurdish, K.LI, ShuSKLUZACEK, Robert
  • 申请人: Alza Corporation
  • 申请人地址: 1900 Charleston Road, M.S. M10-3B Mountain View, CA 94043 US
  • 专利权人: Alza Corporation
  • 当前专利权人: Alza Corporation
  • 当前专利权人地址: 1900 Charleston Road, M.S. M10-3B Mountain View, CA 94043 US
  • 代理机构: Williams, Paul Edwin
  • 优先权: US647864P 20050127
  • 国际公布: WO2006081569 20060803
  • 主分类号: A61K9/28
  • IPC分类号: A61K9/28
ORAL OSMOTIC DOSAGE FORM HAVING A HIGH FLUX MEMBRANE
摘要:
Disclosed are oral osmotic dosage forms and methods wherein a semipermeable membrane of the oral osmotic dosage form includes from about 23 wt% to about 50 wt% of a flux enhancer and from about 0.01 wt% to about 5 wt% of antioxidant, based on the total dry weight of the semi-permeable membrane. Such compositions provide high flux membranes with improved mechanical and transport stability during storage on the shelf.
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