发明授权
- 专利标题： Selurampanel
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申请号： EP06724185.1申请日： 2006-04-10
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公开(公告)号： EP1871749B1公开(公告)日： 2012-08-01
- 发明人: ALLGEIER, Hans , AUBERSON, Yves , CARCACHE, David , FLOERSHEIM, Philipp , GUIBOURDENCHE, Christel , FROESTL, Wolfgang , KALLEN, Jörg , KOLLER, Manuel , MATTES, Henri , NOZULAK, Joachim , ORAIN, David , RENAUD, Johanne
- 申请人： Novartis AG
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： Vögeli-Lange, Regina
- 优先权： GB0507298 20050411
- 国际公布： WO2006108591 20061019
- 主分类号： C07D239/96
- IPC分类号： C07D239/96 ; A61K31/517 ; A61P25/08 ; A61P25/18
摘要：
The present invention relates to l H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as AMPA-receptor ligands, in particular for the treatment of epilepsy or schizophrenia, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) and combinations comprising compounds of formula (I) are disclosed.
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