发明公开
EP1881950A1 NEW COMPOUNDS I 审中-公开
新化合物我

NEW COMPOUNDS I
摘要:
A compound of formula (I), or pharmaceutically acceptable salts thereof wherein X is selected from hydrogen, halo, -CN, -CON2, -CON(C1-6alkyl)H, -CON(C1-6alkyl)2 and heterocyclic groups; R1 is selected from C1-6alkyl and C3-6cycloalkyl; whereby Z is -OH, M is selected from C(O)- , -CH(ORa) , N(Ra) , and S(O)r-, wherein Ra is hydrogen or C1-6alkyl and r is 0, 1 or 2, R2 is selected from C1-6alkyl, C3-6cycloalkyl, heterocycloalkyl, aryl, alkylaryl, and heteroaryl, R2 is substituted with halo, -NO2, -CN, -OH, -CF3, -OCF3, -NH2, and/or -CONH2, when Y is -C1-6alkyl; or Z is -C1-6alkoxy, M is bond, R2 is selected from C1-6alkyl, C3-6cycloalkyl, heterocycloalkyl, aryl, alkylaryl, and heteroaryl, when Y is -C1-6alkoxy.
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