发明公开
EP1883628A2 IMPROVED PROCESS FOR THE PREPARATION OF 3,5-DIETHYL-1,2-DIHYDRO-1-PHENYL-2-PROPYLPYRIDINE
有权
改进方法的3,5-二乙基-1,2-二氢-1-苯基-2-丙基吡啶的制备
- 专利标题: IMPROVED PROCESS FOR THE PREPARATION OF 3,5-DIETHYL-1,2-DIHYDRO-1-PHENYL-2-PROPYLPYRIDINE
- 专利标题(中): 改进方法的3,5-二乙基-1,2-二氢-1-苯基-2-丙基吡啶的制备
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申请号: EP06734700.5申请日: 2006-02-10
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公开(公告)号: EP1883628A2公开(公告)日: 2008-02-06
- 发明人: GRENDZE, Martin , MURUGAN, Ramiah , HUCKSTEP, L., Mark , HOPPER, Charles, R
- 申请人: Vertellus Specialties Inc.
- 申请人地址: 300 N. Meridian Street, Suite 1500 Indianapolis, IN 46024 US
- 专利权人: Vertellus Specialties Inc.
- 当前专利权人: Vertellus Specialties Inc.
- 当前专利权人地址: 300 N. Meridian Street, Suite 1500 Indianapolis, IN 46024 US
- 代理机构: Elsy, David
- 优先权: US651706P 20050210; US651711P 20050210
- 国际公布: WO2006086602 20060817
- 主分类号: C07D213/06
- IPC分类号: C07D213/06
摘要:
Methods are provided for improving production of 3,5-diethyl-l,2-dihydro-l-phenyl-2- propylpyridine (DHP). In one illustrative embodiment, the methods involve controlling the rate of reaction and temperature of the reaction during formation of DHP. In another illustrative embodiment, the methods involve neutralizing the acid catalyst subsequent to DHP formation.
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