发明公开
EP1887008A1 THIENOTRIAZOLODIAZEPINE COMPOUND AND A MEDICINAL USE THEREOF
审中-公开
伊藤OL VER VER ON ON ON ON ON ON ON ON ON ON ON ON ON ON
- 专利标题： THIENOTRIAZOLODIAZEPINE COMPOUND AND A MEDICINAL USE THEREOF
- 专利标题（中）： 伊藤OL VER VER ON ON ON ON ON ON ON ON ON ON ON ON ON ON
-
申请号： EP06756705.7申请日： 2006-05-30
-
公开(公告)号： EP1887008A1公开(公告)日： 2008-02-13
- 发明人: ADACHI, Kunitomo Mitsubishi Tanabe Pharma Corporation , HIKAWA, Hidemasa Mitsubishi Tanabe Pharma Corporation , HAMADA, Maiko Mitsubishi Tanabe Pharma Corporation , ENDOH, Jun-ichi Mitsubishi Tanabe Pharma Corporation , ISHIBUCHI, Seigo Mitsubishi Tanabe Pharma Corporation , FUJIE, Naoto Mitsubishi Tanabe Pharma Corporation , TANAKA, Minoru Mitsubishi Tanabe Pharma Corporation , SUGAHARA, Kunio Mitsubishi Tanabe Pharma Corporation , OSHITA, Kouichi Mitsubishi Tanabe Pharma Corporation , MURATA, Meguru Mitsubishi Tanabe Pharma Corporation
- 申请人： Mitsubishi Tanabe Pharma Corporation
- 申请人地址： 2-10, Dosho-machi 3-chome Chuo-ku Osaka-shi Osaka 541-8505 JP
- 专利权人： Mitsubishi Tanabe Pharma Corporation
- 当前专利权人： Mitsubishi Tanabe Pharma Corporation
- 当前专利权人地址： 2-10, Dosho-machi 3-chome Chuo-ku Osaka-shi Osaka 541-8505 JP
- 代理机构： HOFFMANN EITLE
- 优先权： JP2005157825 20050530
- 国际公布： WO2006129623 20061207
- 主分类号： C07D495/14
- IPC分类号： C07D495/14 ; A61K31/551 ; A61P1/04 ; A61P3/10 ; A61P11/02 ; A61P11/06 ; A61P13/12 ; A61P17/00 ; A61P17/04 ; A61P19/02 ; A61P25/00 ; A61P27/14 ; A61P29/00 ; A61P37/02 ; A61P37/06 ; A61P37/08 ; A61P43/00
摘要：
[Solving means]
A thienotriazolodiazepine compound of the following formula (I)
a pharmaceutical agent containing the compound as an active ingredient, and a production intermediate and a production method of the thienotriazolodiazepine compound.
[Effect]
Since this compound has an inhibitory action on costimulatory signal from CD28 on T cell, it is useful for the prophylaxis or suppression of rejection reaction in transplantation of organ or bone marrow and the like, and the prophylaxis or treatment of autoimmune diseases or allergic diseases.
A thienotriazolodiazepine compound of the following formula (I)
a pharmaceutical agent containing the compound as an active ingredient, and a production intermediate and a production method of the thienotriazolodiazepine compound.
[Effect]
Since this compound has an inhibitory action on costimulatory signal from CD28 on T cell, it is useful for the prophylaxis or suppression of rejection reaction in transplantation of organ or bone marrow and the like, and the prophylaxis or treatment of autoimmune diseases or allergic diseases.
公开/授权文献
- EP1887008B1 THIENOTRIAZOLODIAZEPINE COMPOUND AND A MEDICINAL USE THEREOF 公开/授权日：2021-04-21
信息查询
