发明公开
- 专利标题： FK 228 DERIVATES AS HDAC INHIBITORS
- 专利标题（中）： FK 228作为HDAC抑制剂的衍生物
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申请号： EP06744076.8申请日： 2006-06-02
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公开(公告)号： EP1888097A1公开(公告)日： 2008-02-20
- 发明人: GANESAN, Arasu , PACKHAM, Graham Keith , YUREK-GEORGE, Alexander , CECIL, Alexander, Richard, Liam
- 申请人： UNIVERSITY OF SOUTHAMPTON
- 申请人地址： Highfield Southampton, Hampshire SO17 1BJ GB
- 专利权人： UNIVERSITY OF SOUTHAMPTON
- 当前专利权人： UNIVERSITY OF SOUTHAMPTON
- 当前专利权人地址： Highfield Southampton, Hampshire SO17 1BJ GB
- 代理机构： Perry, Robert Edward
- 优先权： GB0511266 20050602
- 国际公布： WO2006129105 20061207
- 主分类号： A61K38/15
- IPC分类号： A61K38/15 ; A61P35/00
摘要：
Compounds which are FK228 analogues of the general formula (I) or (I/), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.
公开/授权文献
- EP1888097B1 FK 228 DERIVATES AS HDAC INHIBITORS 公开/授权日：2014-03-05
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