发明公开
- 专利标题: METHODS OF AND COMPOSITIONS FOR STIMULATION OF GLUCOSE UPTAKE INTO MUSCLE CELLS AND TREATMENT OF DISEASES
- 专利标题(中): 方法和组合物肌肉刺激的葡萄糖摄取和治疗疾病的
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申请号: EP06760525.3申请日: 2006-05-30
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公开(公告)号: EP1890722A2公开(公告)日: 2008-02-27
- 发明人: LIN, Junyu , KOTHAKOTA, Srinivas , WU, Ge , DOBERSTEIN, Stephen , BRENNAN, Thomas , MASUOKA, Lorianne , QIN, Minmin , MARSHALL, Shannon , WANG, Yan , HOLLENBAUGH, Diane , WILLIAMS, Lewis, T.
- 申请人: Five Prime Therapeutics, Inc.
- 申请人地址: 1650 Owens Street, Suite 200 San Francisco CA 94158-2261 US
- 专利权人: Five Prime Therapeutics, Inc.
- 当前专利权人: Five Prime Therapeutics, Inc.
- 当前专利权人地址: 1650 Owens Street, Suite 200 San Francisco CA 94158-2261 US
- 代理机构: Brasnett, Adrian Hugh
- 优先权: US685702P 20050527; US701490P 20050722; US701964P 20050722; US702065P 20050722; US733791P 20051107; US736866P 20051116; US778169P 20060227; US800443P 20060516; US442244 20060530
- 国际公布: WO2006128125 20061130
- 主分类号: A61K38/20
- IPC分类号: A61K38/20
摘要:
The present invention relates to therapeutic uses of ErbB ligands, including betacellulin. The therapeutic uses include methods of using ErbB ligand family compounds alone, or in conjunction with other agents, for reducing blood glucose levels, treating Type I and Type II diabetes, obesity, muscle wasting diseases, and cardiotoxicity.
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