发明公开
- 专利标题: IL10 SNP ASSOCIATED WITH ACUTE REJECTION
- 专利标题(中): 急性排斥反应相关的SNP IL10
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申请号: EP06754194.6申请日: 2006-06-07
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公开(公告)号: EP1896608A1公开(公告)日: 2008-03-12
- 发明人: ESSIOUX, Laurent , FOERNZLER, Dorothee , HASHIMOTO, Lara , LINDPAINTNER, Klaus , RASHFORD, Michelle , SPLEISS, Olivia , TRUMAN, Matt , VOULGARI, Athina
- 申请人: F. Hoffmann-La Roche AG
- 申请人地址: Grenzacherstrasse 124 4070 Basel CH
- 专利权人: F. Hoffmann-La Roche AG
- 当前专利权人: F. Hoffmann-La Roche AG
- 当前专利权人地址: Grenzacherstrasse 124 4070 Basel CH
- 代理机构: Küng, Peter
- 优先权: EP05105150 20050613
- 国际公布: WO2006133840 20061221
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a polymorphism in the promoter region of the IL 10 gene, optionally in combination with polymorphisms of the MDRl and IMPDH2 genes which were found to be associated with this disease.
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