发明公开
EP1900732A1 NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF
审中-公开
在NALROGENIERTE HETEROCYCLISCHE VERBINDUNG UND SALZ DAVON
- 专利标题: NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF
- 专利标题(中): 在NALROGENIERTE HETEROCYCLISCHE VERBINDUNG UND SALZ DAVON
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申请号: EP06767173.5申请日: 2006-06-22
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公开(公告)号: EP1900732A1公开(公告)日: 2008-03-19
- 发明人: KIYOTO, Taro , TANAKA, Tadashi , TSUTSUI, Yasuhiro , ANDO, Junichi , MOTONO, Mai , KAWAGUCHI, Yasuko , NOGUCHI, Toshiya , USHIKI, Yasunobu , USHIYAMA, Fumihito , URABE, Hiroki
- 申请人: TOYAMA CHEMICAL CO., LTD. , TAISHO PHARMACEUTICAL CO., LTD
- 申请人地址: 2-5, 3-chome, Nishishinjuku, Shinjuku-ku Tokyo 160-0023 JP
- 专利权人: TOYAMA CHEMICAL CO., LTD.,TAISHO PHARMACEUTICAL CO., LTD
- 当前专利权人: TOYAMA CHEMICAL CO., LTD.,TAISHO PHARMACEUTICAL CO., LTD
- 当前专利权人地址: 2-5, 3-chome, Nishishinjuku, Shinjuku-ku Tokyo 160-0023 JP
- 代理机构: Hartz, Nikolai
- 优先权: JP2005184542 20050624; JP2006076850 20060320
- 国际公布: WO2006137485 20061228
- 主分类号: C07D401/06
- IPC分类号: C07D401/06 ; A61K31/4709 ; A61K31/496 ; A61P31/04 ; C07D401/14 ; C07D405/14 ; C07D409/14 ; C07D491/056
摘要:
A nitrogen-containing heterocyclic compound represented by the general formula: wherein the dashed line represents a single bond or a double bond; R 1 , R 2 , R 3 , R 4 and R 5 independently represent a hydrogen atom, halogen atom, a lower alkyl, aryl, lower alkoxy or monocyclic heterocyclic group which may be substituted or the like; R 6 represents a lower alkyl, aryl, monocyclic heterocyclic, bicyclic heterocyclic or tricyclic heterocyclic group which may be substituted; X 1 represents a lower alkylene group or the like; X 2 represents a lower alkylene, lower alkenylene or lower alkynylene group which may be substituted; X 3 represents an oxygen atom, sulfur atom, a sulfinyl group, sulfonyl group or the like; Y 1 represents a bivalent cyclic group, containing a nitrogen, which may be substituted or the like; and Z 1 represents a nitrogen atom, a carbon atom which may be substituted or the like, or a salt thereof. The compound or salt has a potent antibacterial activity and a high safety, and is therefore useful as an excellent antibacterial agent.
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