发明公开
EP1904066A2 COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, AND METHODS OF TREATMENT OF MENOPAUSE AND MOOD, ANXIETY, AND COGNITIVE DISORDERS
有权
艾司佐匹克隆和组合的反式4-（3,4-二氯苯基）-1,2,3,4-四氢-N-甲基-1-萘胺或反式-4-（3,4-二氯苯基）-1,2,4- 3,4-四氢-1-萘胺为绝经，围绝经期和学习障碍于治疗
- 专利标题： COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, AND METHODS OF TREATMENT OF MENOPAUSE AND MOOD, ANXIETY, AND COGNITIVE DISORDERS
- 专利标题（中）： 艾司佐匹克隆和组合的反式4-（3,4-二氯苯基）-1,2,3,4-四氢-N-甲基-1-萘胺或反式-4-（3,4-二氯苯基）-1,2,4- 3,4-四氢-1-萘胺为绝经，围绝经期和学习障碍于治疗
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申请号： EP06786496.7申请日： 2006-07-06
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公开(公告)号： EP1904066A2公开(公告)日： 2008-04-02
- 发明人: CARON, Judy , WESSEL, Thomas , LALJI, Karim , VARNEY, Mark , BAKALE, Roger P. , SINGH, Surendra P. , WILKINSON, H. Scott , SU, Xiping , HAN, Zhengxu , KOENIG, Stephan G.
- 申请人： Sepracor Inc.
- 申请人地址： 84 Waterford Drive Marlborough, Massachusetts 01752 US
- 专利权人： Sepracor Inc.
- 当前专利权人： Sepracor Inc.
- 当前专利权人地址： 84 Waterford Drive Marlborough, Massachusetts 01752 US
- 代理机构： Hutchins, Michael Richard
- 优先权： US697013P 20050706
- 国际公布： WO2007006003 20070111
- 主分类号： A61K31/498
- IPC分类号： A61K31/498
摘要：
One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders.
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