发明授权
- 专利标题： BONE MARROW-DIRECTING DRUG DELIVERY MATERIALS AND THEIR APPLICATIONS
- 专利标题（中）： 骨髓指向药物递送材料及其应用
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申请号： EP06747265.4申请日： 2006-06-05
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公开(公告)号： EP1906924B1公开(公告)日： 2018-05-02
- 发明人: SOU, Keitaro , TAKEOKA, Shinji , TSUCHIDA, Eishun , GOINS, Beth, A. , PHILLIPS, William, T.
- 申请人： WASEDA UNIVERSITY , Board of Regents, The University of Texas System
- 申请人地址： 104, Totsuka-machi 1-chome Shinjuku-ku, Tokyo 169-8050 JP
- 专利权人： WASEDA UNIVERSITY,Board of Regents, The University of Texas System
- 当前专利权人： WASEDA UNIVERSITY,Board of Regents, The University of Texas System
- 当前专利权人地址： 104, Totsuka-machi 1-chome Shinjuku-ku, Tokyo 169-8050 JP
- 代理机构： Nony
- 优先权： JP2005165763 20050606
- 国际公布： WO2006132388 20061214
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K47/12 ; A61K47/34 ; A61K51/00 ; A61P19/02 ; A61P19/08 ; A61P35/00
摘要：
The present invention pertains to a bone marrow-directing drug delivery material that includes at least one fine particle, wherein the fine particle includes an anionic moiety on a surface of the particle. Also disclosed are uses of the material set forth herein for the prevention, treatment, or diagnosis of a disease of bone, cartilage, bone marrow, or a joint. Also disclosed are methods of preventing, treating, or diagnosing a disease of bone, cartilage, bone marrow, or a joint in a subject, involving administering to the subject a pharmaceutically effective amount of the material of the present invention.
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