发明公开
EP1922335A2 TUMOR-ASSOCIATED PEPTIDES BINDING PROMISCUOUSLY TO HUMAN LEUKOCYTE ANTIGEN (HLA) CLASS II MOLECULES 有权
肿瘤相关肽AN混杂人文LEUKOZYTENANTIGEN-(HLA)II类分子结合

  • 专利标题: TUMOR-ASSOCIATED PEPTIDES BINDING PROMISCUOUSLY TO HUMAN LEUKOCYTE ANTIGEN (HLA) CLASS II MOLECULES
  • 专利标题(中): 肿瘤相关肽AN混杂人文LEUKOZYTENANTIGEN-(HLA)II类分子结合
  • 申请号: EP06791838.3
    申请日: 2006-09-05
  • 公开(公告)号: EP1922335A2
    公开(公告)日: 2008-05-21
  • 发明人: DENGJEL, Jörn
  • 申请人: Immatics Biotechnologies GmbH
  • 申请人地址: Paul-Ehrlich-Str. 15 72076 Tübingen DE
  • 专利权人: Immatics Biotechnologies GmbH
  • 当前专利权人: Immatics Biotechnologies GmbH
  • 当前专利权人地址: Paul-Ehrlich-Str. 15 72076 Tübingen DE
  • 代理机构: Krauss, Jan
  • 优先权: EP05019254 20050905
  • 国际公布: WO2007028574 20070315
  • 主分类号: C07K14/47
  • IPC分类号: C07K14/47 A61K39/00
TUMOR-ASSOCIATED PEPTIDES BINDING PROMISCUOUSLY TO HUMAN LEUKOCYTE ANTIGEN (HLA) CLASS II MOLECULES
摘要:
The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 49 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.
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