• 专利标题: KOMBINATIONSTHERAPIE ZUR IMMUNSTIMULATION
  • 专利标题(英): Combination therapy for immunostimulation
  • 申请号: EP05778932.3
    申请日: 2005-08-31
  • 公开(公告)号: EP1928494A2
    公开(公告)日: 2008-06-11
  • 发明人: HOERR, IngmarPASCOLO, Steve
  • 申请人: Curevac GmbH
  • 申请人地址: Paul-Ehrlich-Str. 15 72076 Tübingen DE
  • 专利权人: Curevac GmbH
  • 当前专利权人: Curevac GmbH
  • 当前专利权人地址: Paul-Ehrlich-Str. 15 72076 Tübingen DE
  • 代理机构: Graf von Stosch, Andreas
  • 优先权: DE102004042546 20050831
  • 国际公布: WO2006024518 20060309
  • 主分类号: A61K39/39
  • IPC分类号: A61K39/39 A61P35/00
KOMBINATIONSTHERAPIE ZUR IMMUNSTIMULATION
摘要:
The invention relates to a method for immunostimulation in a mammal, said method consisting of the following steps: a) at least one mRNA containing a region coding for at least one antigen of a pathogen or at least one tumour antigen is administered, and b) at least one cytokine, at least one cytokine-mRNA, at least one CpG DNA or at least one adjuvant RNA is administered. The invention also relates to a product and a kit containing the mRNA and cytokine or cytokine mRNA, or CpG DNA or adjuvant RNA according to the invention.
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