发明公开
EP1939189A1 DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY 审中-公开
DERIVAT MIT PPAR-AGONISTISCHERAKTIVITÄT

DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY
摘要:
A compound of the formula (I):

a pharmaceutically acceptable salt or solvate thereof, wherein
Ring Q is optionally substituted monocyclic aryl, optionally substituted monocyclic heteroaryl, optionally substituted fused aryl or optionally substituted fused heteroaryl,
Y 1 is a bond or -NR 6 - or the like,
Ring A is optionally substituted nonaromatic heterocyclediyl,
a group of the formula: -Y 2 Z 1 - is a group of the formula:


or

R 7 are each independently hydrogen, optionally substituted lower alkyl or the like,
R 8 and R 9 are each independently hydrogen or optionally substituted lower alkyl,
n is an integer between 1 and 3,
Z 1 is a bond, -O-, -S- or -NR 9 -,
Ring B is optionally substituted aromatic carbocyclediyl or optionally substituted aromatic heterocyclediyl,
Y 3 is a bond, optionally substituted lower alkylene optionally intervened by -O-, optionally substituted lower alkenylene or the like, and
Z 2 is COOR 3 or the like.
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