发明公开
- 专利标题： PHOSPHODIESTERASE 10 INHIBITORS
- 专利标题（中）： 磷酸二酯酶10抑制剂
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申请号： EP06801638.5申请日： 2006-08-16
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公开(公告)号： EP1940819A1公开(公告)日： 2008-07-09
- 发明人: ARRINGTON, Mark, Philip , CONTICELLO, Richard, D. , GAUSS, Carla, Maria , HITCHCOOK, Stephen , HOPPER, Allen , LIU, Ruiping , NGUYEN, Truc, Minh , TEHIM, Ashok
- 申请人： Memory Pharmaceuticals Corporation , Amgen Inc.
- 申请人地址： 100 Philips Parkway Montvale, NJ 07645 US
- 专利权人： Memory Pharmaceuticals Corporation,Amgen Inc.
- 当前专利权人： Memory Pharmaceuticals Corporation,Amgen Inc.
- 当前专利权人地址： 100 Philips Parkway Montvale, NJ 07645 US
- 代理机构： Ritter, Thomas Kurt
- 优先权： US708365P 20050816; US719166P 20050922
- 国际公布： WO2007022280 20070222
- 主分类号： C07D401/04
- IPC分类号： C07D401/04 ; C07D403/04 ; C07D403/06 ; C07D495/04 ; C07D471/04 ; A61K31/517 ; A61P25/00 ; A61P3/04
摘要：
Provided are certain quinazolines of formular (I) or (II) that are PDElO inhibitors, pharmaceutical compositions, containing the same and processes for preparing the same. Also provided are methods of treating diseases treatable by PDElO enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like, by administering those certain quinasolines .
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