发明公开
EP1940833A1 INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF
审中-公开
吲唑，苯并噻唑，苯并异噻唑，异恶唑，吡唑并，ISOTHIAZOLOPYRIDINE和其生产和使用
- 专利标题： INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF
- 专利标题（中）： 吲唑，苯并噻唑，苯并异噻唑，异恶唑，吡唑并，ISOTHIAZOLOPYRIDINE和其生产和使用
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申请号： EP06815264.4申请日： 2006-09-22
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公开(公告)号： EP1940833A1公开(公告)日： 2008-07-09
- 发明人: SCHUMACHER, Richard , DANCA, Mihaela Diana , MA, Jianguo , HERBERT, Brian , NGUYEN, Truc Minh , XIE, Wenge , TEHIM, Ashok
- 申请人： Memory Pharmaceuticals Corporation
- 申请人地址： 100 Philips Parkway Montvale, NJ 07645 US
- 专利权人： Memory Pharmaceuticals Corporation
- 当前专利权人： Memory Pharmaceuticals Corporation
- 当前专利权人地址： 100 Philips Parkway Montvale, NJ 07645 US
- 代理机构： Stolmár, Matthias
- 优先权： US719552P 20050923
- 国际公布： WO2007038367 20070405
- 主分类号： C07D453/02
- IPC分类号： C07D453/02 ; A61K31/435 ; A61P25/00
摘要：
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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