发明公开
EP1953152A1 Process for preparing quinazoline RHO-kinase inhibitors and intermediates thereof
审中-公开
Verfahren zur Herstellung von RHO-kinaseinhibierenden Chinazolinen und Zwischenproduktendafür
- 专利标题： Process for preparing quinazoline RHO-kinase inhibitors and intermediates thereof
- 专利标题（中）： Verfahren zur Herstellung von RHO-kinaseinhibierenden Chinazolinen und Zwischenproduktendafür
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申请号： EP08103780.6申请日： 2003-09-24
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公开(公告)号： EP1953152A1公开(公告)日： 2008-08-06
- 发明人: Bankston, Donald , Nagarathnam, Dhanaphalan , Asgari, Davoud , Shao, Jianxing , Liu, Xiao-Gao , Khire, Uday , Wang, Chunguang , Hart, Barry , Boyer, Stephen , Weber, Olaf , Lynch, Mark
- 申请人： BAYER CORPORATION
- 申请人地址： 100 Bayer Road Pittsburgh, PA 15205 US
- 专利权人： BAYER CORPORATION
- 当前专利权人： BAYER CORPORATION
- 当前专利权人地址： 100 Bayer Road Pittsburgh, PA 15205 US
- 代理机构： Ziebig, Marlene
- 优先权： US252369 20020924
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; C07D215/22 ; C07D405/14 ; C07D403/14 ; C07D401/14 ; C07D405/04 ; C07D403/04 ; C07D401/04
摘要：
The present invention relates to methods of producing quinazoline compounds and derivatives thereof which are useful as Rho-kinase Inhibitors or intermediates thereof. Rho-kinase inhibitors are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
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