发明公开
EP1957491A2 PYRROLO (2,3-B) PYRIDINE DERIVATIVES USEFUL AS TEC KINASE INHIBITORS
审中-公开
PYROLLO吡啶衍生物NUTZLICH ALS TEC-KINASE-INHIBITOREN
- 专利标题： PYRROLO (2,3-B) PYRIDINE DERIVATIVES USEFUL AS TEC KINASE INHIBITORS
- 专利标题（中）： PYROLLO吡啶衍生物NUTZLICH ALS TEC-KINASE-INHIBITOREN
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申请号： EP06837092.3申请日： 2006-11-07
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公开(公告)号： EP1957491A2公开(公告)日： 2008-08-20
- 发明人: BENTZIEN, Joerg, Martin , TAKAHASHI, Hidenori
- 申请人： Boehringer Ingelheim International GmbH , Boehringer Ingelheim Pharma GmbH & Co. KG
- 申请人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人： Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 代理机构： Hammann, Heinz
- 优先权： US735471P 20051112
- 国际公布： WO2007058832 20070524
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61P29/00 ; A61P37/00
摘要：
Disclosed are compounds of formula (I), wherein Q, R1, R2, R3, R4 and R5 are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
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