发明公开
EP1959986A2 GLUCAGON ANALOGS EXHIBITING PHYSIOLOGICAL SOLUBILITY AND STABILITY
有权
胰高血糖素类似物与生理学的溶解性和稳定性
- 专利标题： GLUCAGON ANALOGS EXHIBITING PHYSIOLOGICAL SOLUBILITY AND STABILITY
- 专利标题（中）： 胰高血糖素类似物与生理学的溶解性和稳定性
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申请号： EP06827600.5申请日： 2006-11-06
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公开(公告)号： EP1959986A2公开(公告)日： 2008-08-27
- 发明人: DIMARCHI, Richard, D. , SMILEY, David, L.
- 申请人： Indiana University Research and Technology Corporation
- 申请人地址： 351 West 10th Street Indianapolis IN 46202 US
- 专利权人： Indiana University Research and Technology Corporation
- 当前专利权人： Indiana University Research and Technology Corporation
- 当前专利权人地址： 351 West 10th Street Indianapolis IN 46202 US
- 代理机构： Elsy, David
- 优先权： US734307P 20051107
- 国际公布： WO2007056362 20070518
- 主分类号： A61K38/26
- IPC分类号： A61K38/26
摘要：
Modified glucagon peptides are disclosed having improved solubility and stability, wherein the native glucagon peptide has been modified by pegylation, or the addition of a carboxy terminal peptide selected from the group consisting of SEQ ID NO: 19, SEQ ID NO: 20, SEQ ID NO: 21, or both.
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