发明授权
- 专利标题： BOTULINUM NANOEMULSIONS
- 专利标题（中）： 肉骨粉纳米乳液
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申请号： EP06851782.0申请日： 2006-12-01
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公开(公告)号： EP1959994B1公开(公告)日： 2017-08-30
- 发明人: EDELSON, Jonathan , NICOLOSI, Robert
- 申请人： UNIVERSITY OF MASSACHUSETTS LOWELL
- 申请人地址： One Beacon Street 31st Floor Boston, MA 02108 US
- 专利权人： UNIVERSITY OF MASSACHUSETTS LOWELL
- 当前专利权人： UNIVERSITY OF MASSACHUSETTS LOWELL
- 当前专利权人地址： One Beacon Street 31st Floor Boston, MA 02108 US
- 代理机构： Ruiz Antoli, Soledad Cecilia
- 优先权： US741139P 20051201
- 国际公布： WO2008045107 20080417
- 主分类号： A61K39/08
- IPC分类号： A61K39/08 ; B82Y5/00 ; A61K8/34 ; A61Q19/08 ; A61K8/06 ; A61K38/48 ; A61K8/64
摘要：
The embodiment described herein are related nanoemulsions comprising botulinum toxins, surfactant and oil. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.
公开/授权文献
- EP1959994A2 BOTULINUM NANOEMULSIONS 公开/授权日：2008-08-27
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