发明公开
EP1965862A2 COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT
审中-公开
组合的H3拮抗剂/反相激动剂和食欲
- 专利标题: COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT
- 专利标题(中): 组合的H3拮抗剂/反相激动剂和食欲
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申请号: EP06847740.5申请日: 2006-12-18
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公开(公告)号: EP1965862A2公开(公告)日: 2008-09-10
- 发明人: VAN HEEK, Margaret , HWA, Joyce, J. , GRAZIANO, Michael, P. , LACHOWICZ, Jean, E. , KOWALSKI, Timothy, J. , VELTRI, Enrico, P. , MCCORMICK, Kevin, D. , BERLIN, Michael, Y. , ASLANIAN, Robert, G.
- 申请人: Schering Corporation
- 申请人地址: 2000 Galloping Hill Road Kenilworth, NJ 07033-0530 US
- 专利权人: Schering Corporation
- 当前专利权人: Schering Corporation
- 当前专利权人地址: 2000 Galloping Hill Road Kenilworth, NJ 07033-0530 US
- 代理机构: HOFFMANN EITLE
- 优先权: US752323P 20051221
- 国际公布: WO2007075555 20070705
- 主分类号: A61P3/04
- IPC分类号: A61P3/04 ; A61P3/10 ; A61K45/06
摘要:
The present invention relates to pharmaceutical compositions comprising therapeutic combinations comprising: one or more H3 antagonists/inverse agonists; one or more appetite suppressants selected from the group consisting of CBi antagonists/inverse agonists, sibutramine, phentermine and topiramate; and option one or more HMG-CoA reductase inhibitors. The invention also relates to medicaments and kits comprising the pharmaceutical compositions of the present invention, and methods of treating obesity, obesity related disorders and diabetes using the pharmaceutical compositions of the present invention.
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