发明公开
EP1967200A1 Formulations of alpha-amylase inhibitors of P. vulgaris with alpha-glucosidade inhibitores of S. oblonga or S. reticulata useful in the treatment of diabetes and obesity
审中-公开
从P.α-淀粉酶抑制剂的制剂与S矩或S.网状的α-葡萄糖苷酶抑制剂为寻常糖尿病和肥胖症的治疗
- 专利标题： Formulations of alpha-amylase inhibitors of P. vulgaris with alpha-glucosidade inhibitores of S. oblonga or S. reticulata useful in the treatment of diabetes and obesity
- 专利标题（中）： 从P.α-淀粉酶抑制剂的制剂与S矩或S.网状的α-葡萄糖苷酶抑制剂为寻常糖尿病和肥胖症的治疗
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申请号： EP07425134.9申请日： 2007-03-07
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公开(公告)号： EP1967200A1公开(公告)日： 2008-09-10
- 发明人: Bombardelli, Ezio , Morazzoni, Paolo , Ponzone, Cesare , Ronchi, Massimo
- 申请人： Indena S.p.A.
- 申请人地址： Via Ortles, 12 20139 Milano IT
- 专利权人： Indena S.p.A.
- 当前专利权人： Indena S.p.A.
- 当前专利权人地址： Via Ortles, 12 20139 Milano IT
- 代理机构： Minoja, Fabrizio
- 主分类号： A61K36/48
- IPC分类号： A61K36/48 ; A61K36/37 ; A23L1/305 ; A23L1/30
摘要：
This invention relates to the combination of α-amylase inhibitors prepared from Phaseolus vulgaris with α-glucosidase inhibitors obtained from Salacia oblonga and other species. The α-amylase inhibitor is accompanied by a quantity of lectins that reduces the amount of glucose originating from the starches present in the diet, and considerably reduces the appetite after repeated administration. The combination with α-glucosidase inhibitors, such as extracts of Salacia or the thiosugars present in it, further reduce the blood glucose, acting synergically, and consequently reduce the synthesis of fats from carbohydrates.
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