发明公开
- 专利标题： TETRALONE-BASED MONOAMINE REUPTAKE INHIBITORS
- 专利标题（中）： 单胺再摄取抑制剂对TETRALONBASIS
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申请号： EP06848050.8申请日： 2006-12-21
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公开(公告)号： EP1978961A2公开(公告)日： 2008-10-15
- 发明人: SHAO, Liming , WANG, Fengjiang , MALCOLM, Scott, Christopher , HEWITT, Michael, Charles , BUSH, Larry, R. , VARNEY, Mark , CAMPBELL, Una , ENGEL, Sharon, Rae , HARDY, Larry, Wendell , KOCH, Patrick , MA, Jianguo
- 申请人： SEPRACOR, INC.
- 申请人地址： 84 Waterford Drive Marlborough, MA 01752-7010 US
- 专利权人： SEPRACOR, INC.
- 当前专利权人： SEPRACOR, INC.
- 当前专利权人地址： 84 Waterford Drive Marlborough, MA 01752-7010 US
- 代理机构： Harrison Goddard Foote
- 优先权： US756555P 20060106
- 国际公布： WO2007081542 20070719
- 主分类号： A61K31/4706
- IPC分类号： A61K31/4706
摘要：
The invention relates to novel tetralone based amines and their use in the treatment of central nervous system (CNS) disorders, such as depression, attention deficit hyperactivity disorder (ADHD) and Parkinson's disease. The invention further relates to pharmaceutical compositions containing the compounds and compositions of the invention as well as methods of inhibiting reuptake of one or more monoamine, such as such as dopamine and norepinephrine, from the synaptic cleft, and methods of modulating one or more monoamine transporter.
公开/授权文献
- EP1978961B1 TETRALONE-BASED MONOAMINE REUPTAKE INHIBITORS 公开/授权日：2016-03-16
信息查询
IPC分类:
