Systems and methods for high-speed variable printing are provided. Ink jet technology and lithographic systems may be combined in such a way to create a fully variable and high-quality print system. An aqueous solution is applied to a cylinder to produce a negative image. The aqueous solution may comprise a block copolymer capable of physical bonding with the cylinder. Ink is then applied to the cylinder, and a positive image is transferred in ink to a print medium. The systems and methods described herein may be used to create high-quality one-to-one marketing applications.