发明公开
EP1997832A1 Monoclonal antibodies against Claudin-18 for treatment of cancer
审中-公开
MonoklonaleAntikörpergegen Claudin-18 zur Behandlung von Krebs
- 专利标题： Monoclonal antibodies against Claudin-18 for treatment of cancer
- 专利标题（中）： MonoklonaleAntikörpergegen Claudin-18 zur Behandlung von Krebs
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申请号： EP07010622.4申请日： 2007-05-29
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公开(公告)号： EP1997832A1公开(公告)日： 2008-12-03
- 发明人: Sahin, Ugur , Türeci, Özlem , Brandenburg, Gunda , Usener, Dirk
- 申请人： Ganymed Pharmaceuticals AG , Johannes Gutenberg-Universität Mainz
- 申请人地址： Freiligrathstr. 12 55131 Mainz DE
- 专利权人： Ganymed Pharmaceuticals AG,Johannes Gutenberg-Universität Mainz
- 当前专利权人： Ganymed Pharmaceuticals AG,Johannes Gutenberg-Universität Mainz
- 当前专利权人地址： Freiligrathstr. 12 55131 Mainz DE
- 代理机构： Schnappauf, Georg
- 主分类号： C07K16/30
- IPC分类号： C07K16/30 ; A61K39/395 ; A61P35/00 ; C12N5/12 ; A61K47/48
摘要：
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, cancer of the gallbladder, and the metastases thereof.
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