发明公开
- 专利标题: COMPOSITIONS AND METHODS OF USE FOR ANTIBODIES OF C-MET
- 专利标题(中): 组合物及其使用C-MET抗体的方法
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申请号: EP07754114.2申请日: 2007-03-29
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公开(公告)号: EP2004693A2公开(公告)日: 2008-12-24
- 发明人: STOVER, David Raymond , PRASSLER, Josef , BERGER, Catrin , BROCKS, Bodo
- 申请人: NOVARTIS AG , Novartis Pharma GmbH
- 申请人地址: Lichtstrasse 35 4056 Basel CH
- 专利权人: NOVARTIS AG,Novartis Pharma GmbH
- 当前专利权人: NOVARTIS AG,Novartis Pharma GmbH
- 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
- 代理机构: Nash, Guy Cameron
- 优先权: US787556P 20060330
- 国际公布: WO2007126799 20071108
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K39/395 ; A61P35/00 ; A61P29/00 ; G01N33/00 ; C12N15/13 ; C12N15/85 ; A61K47/48 ; A61K38/00 ; A61K31/00
摘要:
Antibodies and fragments that bind to the protein target c Met, particularly to epitopes located in the c Met extracellular domain, are provided, as are methods of use of the antibodies and kits, for treating an unwanted cell, in particular, a cell associated with a c Met-related condition such as a cancer, a metastasis, or an inflammatory condition.
公开/授权文献
- EP2004693B1 COMPOSITIONS AND METHODS OF USE FOR ANTIBODIES OF C-MET 公开/授权日:2012-06-06
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