This disclosure describes signal processing techniques that can improve the performance of blind source separation (BSS) techniques. In particular, the described techniques propose pre-processing steps that can help to de-correlate the different signals from one another prior to execution of the BSS techniques. In addition, the described techniques also propose optional post-processing steps that can further de-correlate the different signals following execution of the BSS techniques. The techniques may be particularly useful for improving BSS performance with highly correlated audio signals, e.g., from two microphones that are in close spatial proximity to one another.