发明公开
- 专利标题： IMPROVED GENE SILENCING METHODS
- 专利标题（中）： 改进的基因沉默方法
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申请号： EP07718830.8申请日： 2007-05-03
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公开(公告)号： EP2018420A1公开(公告)日： 2009-01-28
- 发明人: WATERHOUSE, Peter , WANG, Ming-Bo
- 申请人： COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
- 申请人地址： Limestone Avenue Campbell, Australian Capital Territory 2612 AU
- 专利权人： COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
- 当前专利权人： COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
- 当前专利权人地址： Limestone Avenue Campbell, Australian Capital Territory 2612 AU
- 代理机构： Almond-Martin, Carol
- 优先权： EP06075995 20060503; US798020P 20060504
- 国际公布： WO2007128052 20071115
- 主分类号： C12N5/14
- IPC分类号： C12N5/14 ; C12N15/29 ; C12N15/82
摘要：
Methods and means are provided to modulate gene silencing in eukaryotes through the alteration of the functional level of particular DICER or DICER like proteins. Also provided are methods and means to modulate post-transcriptional gene silencing in eukaryotes through the alteration of the functional level of proteins involved in transcriptional silencing of the silencing RNA encoding genes.
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