发明公开
EP2023952A2 INDUCING IMMUNE RESPONSES TO INFLUENZA VIRUS USING POLYPEPTIDE AND NUCLEIC ACID COMPOSITIONS
有权
免疫反应诱导流感病毒和使用POLYPEPITD-核酸组合物
- 专利标题： INDUCING IMMUNE RESPONSES TO INFLUENZA VIRUS USING POLYPEPTIDE AND NUCLEIC ACID COMPOSITIONS
- 专利标题（中）： 免疫反应诱导流感病毒和使用POLYPEPITD-核酸组合物
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申请号： EP07867125.2申请日： 2007-05-18
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公开(公告)号： EP2023952A2公开(公告)日： 2009-02-18
- 发明人: ALEXANDER, Jeffery L. , BILSEL, Pamuk A. , NEWMAN, Mark J.
- 申请人： Pharmexa Inc.
- 申请人地址： 5820 Nancy Ridge Drive San Diego, CA 92121 US
- 专利权人： Pharmexa Inc.
- 当前专利权人： Pharmexa Inc.
- 当前专利权人地址： 5820 Nancy Ridge Drive San Diego, CA 92121 US
- 代理机构： Inspicos A/S
- 优先权： US801065P 20060518; US838859P 20060821
- 国际公布： WO2008054540 20080508
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/42
摘要：
The present invention provides polynucleotides and polypeptides capable of enhancing the immune response of a human in need of protection against influenza virus infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an influenza protein or a fragment, variant, or derivative thereof, or at least one polypeptide encoded therefrom. The present invention also relates to identifying and preparing influenza virus epitopes and to polynucleotides and polypeptides comprising such influenza virus epitopes. The present invention also relates to compositions and methods of use in the prevention and treatment of influenza virus infection.
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