发明公开
- 专利标题： COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
- 专利标题（中）： 化合物和组合物作为蛋白激酶抑制剂
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申请号： EP07797441.8申请日： 2007-05-11
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公开(公告)号： EP2027123A2公开(公告)日： 2009-02-25
- 发明人: REN, Pingda , WU, Baogen , ZHANG, Guobao , XIE, Yongping , OKRAM, Barun , NIKULIN, Victor , WANG, Xia , CHOI, Ha-soon
- 申请人： IRM LLC
- 申请人地址： Hurst Holme, 12 Trott Road Hamilton, HM 11 BM
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： Hurst Holme, 12 Trott Road Hamilton, HM 11 BM
- 代理机构： Kiddle, Simon John
- 优先权： US799779P 20060511
- 国际公布： WO2007134259 20071122
- 主分类号： C07D471/14
- IPC分类号： C07D471/14 ; A61K31/4375
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the AbI, Bcr-Abl, Bcr-Abl(T315I), ALK5BLK, BMX, BRK, C-kit, c-RAF, CSK, c-SRC, EGFR, Fes, FGFR3, Flt3, Fms, Fyn, IGF-IR, IR, JAK(2), JAK(3), KDR, Lck, NLK, p70S6K, PDGFRα, Ros, SAPK2α, SGK, SIK, Syk, Tie2 and TrkB kinases.
公开/授权文献
- EP2027123B1 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS 公开/授权日：2011-02-23
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