A cryopreservation storage device (100), in particular for cryopreservation of biological samples, comprises a plurality of multi sample modules (20) being adapted for accommodating the biological samples and sample memories, a module control device (30) controlling an access to sample memories accommodated by the multi sample modules (20) , and a data interface (41) for accessing to the module control device (30), wherein the module control device (30) includes a data management processor (31), which can be controlled via the data interface (41) . Furthermore, a cryopreservation apparatus including at least one cryopreservation storage device (100) and a method for cryopreservation of biological samples are described.