发明公开
EP2029584A2 2-[3H-THIAZOL-2-YLIDINEMETHYL]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE
审中-公开
2- [3H-噻唑-2- YLIDINMETHYL]吡啶和相关化合物及其用途
- 专利标题： 2-[3H-THIAZOL-2-YLIDINEMETHYL]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE
- 专利标题（中）： 2- [3H-噻唑-2- YLIDINMETHYL]吡啶和相关化合物及其用途
-
申请号： EP07705241.3申请日： 2007-02-21
-
公开(公告)号： EP2029584A2公开(公告)日： 2009-03-04
- 发明人: BROWN, Robert , PLUMB, Jane , AHERNE, Gladys, Wynne , MCDONALD, Edward , JONES, Keith , HILTON, Stephen
- 申请人： Cancer Research Technology Limited
- 申请人地址： Sardinia House, Sardinia Street London WC2A 3NL GB
- 专利权人： Cancer Research Technology Limited
- 当前专利权人： Cancer Research Technology Limited
- 当前专利权人地址： Sardinia House, Sardinia Street London WC2A 3NL GB
- 代理机构： Wytenburg, Wilhelmus Johannes
- 优先权： GB0603455 20060221
- 国际公布： WO2007096618 20070830
- 主分类号： C07D417/06
- IPC分类号： C07D417/06 ; C07D513/04 ; A61K31/4439 ; A61P35/00
摘要：
The present invention pertains to certain 2-[3H-thiazol-2-ylidinemethyl]pyridine compounds and analogs thereof, which, inter alia, inhibit cell proliferation, treat cancer, etc., and more specifically to compounds of the following formula, wherein RA1, RA2, RA3, RA4, RB1, RB2, RNA, RNB, and X- are as defined herein. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative conditions such as cancer, etc.
信息查询
