发明公开
EP2029748A2 PROTÉINES DE FUSION PROTÉINE N D'UN VIRUS DE LA FAMILLE DES PARAMYXOVIRIDAE-PROTÉINE D'INTÉRÊT
有权
融合蛋白BETWEEN A N蛋白质的病毒从PARAMYOVIRIDAE AND A INTERESTPROTEIN家族
- 专利标题: PROTÉINES DE FUSION PROTÉINE N D'UN VIRUS DE LA FAMILLE DES PARAMYXOVIRIDAE-PROTÉINE D'INTÉRÊT
- 专利标题(英): N protein fusion proteins of a virus in the paramyxoviridae-protein of interest family and their uses for vaccination and intra-cellular vectorisation
- 专利标题(中): 融合蛋白BETWEEN A N蛋白质的病毒从PARAMYOVIRIDAE AND A INTERESTPROTEIN家族
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申请号: EP07731315.3申请日: 2007-04-18
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公开(公告)号: EP2029748A2公开(公告)日: 2009-03-04
- 发明人: ELEOUËT, Jean-François , RIFFAULT, Sabine
- 申请人: Institut National de la Recherche Agronomique
- 申请人地址: 147, Rue de l'Université 75338 Paris Cedex 07 FR
- 专利权人: Institut National de la Recherche Agronomique
- 当前专利权人: Institut National de la Recherche Agronomique
- 当前专利权人地址: 147, Rue de l'Université 75338 Paris Cedex 07 FR
- 代理机构: Jacobson, Claude
- 优先权: FR0603410 20060418
- 国际公布: WO2007119011 20071025
- 主分类号: C12N15/62
- IPC分类号: C12N15/62 ; C12N15/45 ; C07K14/135 ; A61K39/155 ; C07K14/115 ; A61K47/48
摘要:
The invention relates to N protein fusion proteins of interest, possibly in the form of N protein protein of interest/P protein soluble complexes, the N and P proteins being proteins of a virus in the Paramyxoviridae family. When the protein of interest is an antigen, the invention also relates to vaccine compositions and reagents of the diagnostic comprising these N protein-antigen fusion proteins or these N protein-antigen/P protein complexes. The N protein-protein of interest fusion may also be used as a 'vector' to transport therapeutic molecules of interest in the cells, such as antiviral or anticancer molecules.
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