发明公开
- 专利标题： NEW CXCR2 INHIBITORS
- 专利标题（中）： 新CXCR2抑制剂
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申请号： EP07785841.3申请日： 2007-06-25
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公开(公告)号： EP2040688A1公开(公告)日： 2009-04-01
- 发明人: HACHTEL, Stephanie , DEDIO, Juergen , DEFOSSA, Elisabeth , GRUENEBERG, Sven , HEITSCH, Holger , BOCK, William , CHEN, Charlie , KOSLEY, Raymond , KUNG, Chung-Yi , PATEK, Marcel , SHER, Rosy , SHIMSHOCK, Stephen , WEICHSEL, Aleksandra
- 申请人： Sanofi-Aventis
- 申请人地址： 174 Avenue de France 75013 Paris FR
- 专利权人： Sanofi-Aventis
- 当前专利权人： Sanofi-Aventis
- 当前专利权人地址： 174 Avenue de France 75013 Paris FR
- 代理机构： Löschner, Thomas
- 优先权： EP06013323 20060628
- 国际公布： WO2008000409 20080103
- 主分类号： A61K31/166
- IPC分类号： A61K31/166 ; A61P29/00 ; C07C235/66 ; C07D215/24 ; C07D333/64 ; C07D213/30
摘要：
The invention relates to compounds of the formula (I), in which R1, R2, X, A, B, Z and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
公开/授权文献
- EP2040688B1 NEW CXCR2 INHIBITORS 公开/授权日：2014-04-02
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