发明公开
EP2041135A1 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7
审中-公开
为代理TLR7 8 OXOADENINDERIVATE的调节剂
- 专利标题： 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7
- 专利标题（中）： 为代理TLR7 8 OXOADENINDERIVATE的调节剂
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申请号： EP07748310.5申请日： 2007-07-03
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公开(公告)号： EP2041135A1公开(公告)日： 2009-04-01
- 发明人: COOK, Anthony , MCINALLY, Tom , THOM, Stephen , WADA, Hiroki
- 申请人： Astra Zeneca AB , Dainippon Sumitomo Pharma Co., Ltd.
- 申请人地址： 151 85 Södertälje SE
- 专利权人： Astra Zeneca AB,Dainippon Sumitomo Pharma Co., Ltd.
- 当前专利权人： Astra Zeneca AB,Dainippon Sumitomo Pharma Co., Ltd.
- 当前专利权人地址： 151 85 Södertälje SE
- 优先权： US818554P 20060705
- 国际公布： WO2008004948 20080110
- 主分类号： C07D473/18
- IPC分类号： C07D473/18 ; A61K31/522 ; A61P11/00 ; A61P11/06 ; A61P17/00 ; A61P27/14 ; A61P31/14 ; A61P31/18 ; A61P31/20 ; A61P35/00 ; A61P37/08
摘要：
The present invention provides 8-oxoadenine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The 8-oxoadenine derivatives act as modulators of Toll-like Receptor (TLR) 7 and thus may be used in the treatment of asthma, hepatitis, allergic diseases, viral and bacterial infection as well as cancer.
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