发明授权
EP2043616B1 N-TERMINAL CONJUGATION OF POLYSIALIC ACID TO PROTEINS
有权
KUPPLUNG VONPOLYSIALINSÄUREAM N-TERMINUS VON PROTEINEN
- 专利标题: N-TERMINAL CONJUGATION OF POLYSIALIC ACID TO PROTEINS
- 专利标题(中): KUPPLUNG VONPOLYSIALINSÄUREAM N-TERMINUS VON PROTEINEN
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申请号: EP07766361.5申请日: 2007-07-25
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公开(公告)号: EP2043616B1公开(公告)日: 2016-01-27
- 发明人: JAIN, Sanjay , LAING, Peter , GREGORIADIS, Gregory
- 申请人: Lipoxen Technologies Limited
- 申请人地址: London BioScience Innovation Centre 2 Royal College Street London NW1 0NH GB
- 专利权人: Lipoxen Technologies Limited
- 当前专利权人: Lipoxen Technologies Limited
- 当前专利权人地址: London BioScience Innovation Centre 2 Royal College Street London NW1 0NH GB
- 代理机构: Schlich, George
- 优先权: EP06117830 20060725
- 国际公布: WO2008012540 20080131
- 主分类号: A61K47/48
- IPC分类号: A61K47/48 ; C07K17/12 ; C07K1/107 ; C07K14/535 ; C07K14/555 ; C07K14/59
摘要:
A composition comprises a population of polysaccharide derivatives of a protein, wherein the protein is insulin or an insulin-like protein and the polysaccharide is anionic and comprises between 2 and 125 saccharide units, and wherein the population consists substantially only of derivatives of the protein derivatised at the N-terminal of the B-chain.
公开/授权文献
- EP2043616A1 N-TERMINAL DERIVATISATION OF PROTEINS WITH POLYSACCHARIDES 公开/授权日:2009-04-08
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