发明公开
EP2044072A1 AMINO-IMIDAZOLONES AND THEIR USE AS A MEDICAMENT FOR TREATING COGNITIVE IMPAIRMENT, ALZHEIMER DISEASE, NEURODEGENERATION AND DEMENTIA
审中-公开
氨基咪唑啉酮及其作为药物治疗认知障碍,阿尔茨海默病,神经退化和痴呆的药物
- 专利标题: AMINO-IMIDAZOLONES AND THEIR USE AS A MEDICAMENT FOR TREATING COGNITIVE IMPAIRMENT, ALZHEIMER DISEASE, NEURODEGENERATION AND DEMENTIA
- 专利标题(中): 氨基咪唑啉酮及其作为药物治疗认知障碍,阿尔茨海默病,神经退化和痴呆的药物
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申请号: EP07748237.0申请日: 2007-06-12
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公开(公告)号: EP2044072A1公开(公告)日: 2009-04-08
- 发明人: BERG, Stefan , HOLENZ, Jörg , HÖGDIN, Katharina , KOLMODIN, Karin , PLOBECK, Niklas , ROTTICCI, Didier , SEHGELMEBLE, Fernando , EK, Maria
- 申请人: AstraZeneca AB , Astex Therapeutics Limited
- 申请人地址: 151 85 Södertälje SE
- 专利权人: AstraZeneca AB,Astex Therapeutics Limited
- 当前专利权人: AstraZeneca AB,Astex Therapeutics Limited
- 当前专利权人地址: 151 85 Södertälje SE
- 优先权: US813539P 20060614; US896984P 20070326
- 国际公布: WO2007145571 20071221
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/519 ; A61P25/28
摘要:
This invention relates to novel compounds having the structural formula (I) below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
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