发明公开
- 专利标题： BRIDGED DIAZEPAN OREXIN RECEPTOR ANTAGONISTS
- 专利标题（中）： 桥联柴胡素OREXIN受体拮抗剂
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申请号： EP07796851.9申请日： 2007-07-13
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公开(公告)号： EP2049110A2公开(公告)日： 2009-04-22
- 发明人: COLEMAN, Paul, J. , COX, Christopher, D. , MCGAUGHEY, Georgia, B. , ROECKER, Anthony, J. , SCHREIER, John, D.
- 申请人： Merck & Co., Inc.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Buchan, Gavin MacNicol
- 优先权： US831178P 20060714
- 国际公布： WO2008008517 20080117
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D471/08 ; A61P3/04
摘要：
The present invention is directed to bridged diazepan compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
公开/授权文献
- EP2049110B1 BRIDGED DIAZEPAN OREXIN RECEPTOR ANTAGONISTS 公开/授权日：2014-08-20
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