发明公开
EP2049679A2 METHODS AND MATERIALS FOR IN VITRO ANALYSIS AND/OR USE OF MEMBRANE-ASSOCIATED PROTEINS, PORTIONS THEREOF OR VARIANTS THEREOF
审中-公开
方法和材料体外分析和/或资金从膜相关的蛋白质，其一部分或其变型应用
- 专利标题： METHODS AND MATERIALS FOR IN VITRO ANALYSIS AND/OR USE OF MEMBRANE-ASSOCIATED PROTEINS, PORTIONS THEREOF OR VARIANTS THEREOF
- 专利标题（中）： 方法和材料体外分析和/或资金从膜相关的蛋白质，其一部分或其变型应用
-
申请号： EP07835911.4申请日： 2007-06-28
-
公开(公告)号： EP2049679A2公开(公告)日： 2009-04-22
- 发明人: WEIS, Robert, M. , SHROUT, Anthony, L. , ESPOSITO, Edward, A.
- 申请人： P.A. Technologies LLC
- 申请人地址： 101 University Drive, Suite A5 Amherst, MA 01002 US
- 专利权人： P.A. Technologies LLC
- 当前专利权人： P.A. Technologies LLC
- 当前专利权人地址： 101 University Drive, Suite A5 Amherst, MA 01002 US
- 代理机构： Atkinson, Peter Birch
- 优先权： US816944P 20060628
- 国际公布： WO2008002656 20080103
- 主分类号： C12Q1/50
- IPC分类号： C12Q1/50
摘要：
Methods and materials use template-directed assembly of polypeptides and optionally additional reagents to analyze the functionality of membrane-associated proteins, such as, for example, portions of transmembrane proteins, membrane-associated proteins, and others proteins that bind to transmembrane proteins and membrane-associated proteins, and to analyze the effect of test compounds or mutations on the functionality of same. The methods and materials of the present application provide a more native-like environment for analyzing the functionality of membrane- associated proteins, and thus provide effective tools for studies involving the detection of the level of enzyme activity of such proteins in an environment that closely resembles the native environment in the cell, and for novel manufacturing processes.
信息查询
