发明公开
- 专利标题： Anti-P selectin antibodies
- 专利标题（中）： Antikörpergegen P-Selectin
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申请号： EP09156071.4申请日： 2005-04-05
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公开(公告)号： EP2067789A1公开(公告)日： 2009-06-10
- 发明人: Graus, Yvo , Himber, Jacques , Jansen-Molenaar, Miranda , Kling, Dorothee , Kopetzky, Erhard , Parren, Paul , Rebers, Frank , Steiner, Beat , Stern, Anne , Strein, Pamela , Stubenrauch, Kay-Gunnar , Van de Winkel, Jan , Van Vugt, Martine
- 申请人： F. Hoffmann-La Roche AG
- 申请人地址： Grenzacherstrasse 124 4070 Basel CH
- 专利权人： F. Hoffmann-La Roche AG
- 当前专利权人： F. Hoffmann-La Roche AG
- 当前专利权人地址： Grenzacherstrasse 124 4070 Basel CH
- 代理机构： Heiroth, Ulrike Hildegard
- 优先权： EP04008722 20040413
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K16/46 ; A61K39/395 ; C12N5/12 ; C12N15/63
摘要：
This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor Clq. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).
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