发明公开
EP2080770A1 Proteinaceous binding molecules comprising purification tags
审中-公开
ProteinöseBindemolekülemit Reinigungstags
- 专利标题： Proteinaceous binding molecules comprising purification tags
- 专利标题（中）： ProteinöseBindemolekülemit Reinigungstags
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申请号： EP08100707.2申请日： 2008-01-21
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公开(公告)号： EP2080770A1公开(公告)日： 2009-07-22
- 发明人: Steidl, Stefan
- 申请人： MorphoSys AG
- 申请人地址： Lena-Christ-Strasse 48 82152 Martinsried/München DE
- 专利权人： MorphoSys AG
- 当前专利权人： MorphoSys AG
- 当前专利权人地址： Lena-Christ-Strasse 48 82152 Martinsried/München DE
- 代理机构： Hutter, Bernd
- 主分类号： C07K14/435
- IPC分类号： C07K14/435 ; C07K16/46
摘要：
The present invention provides proteinaceous binding molecules, in particular antibodies, having at least two variable domains. One variable domain binds to a target molecule of interest. At least one other variable domain comprises a purification tag suitable for purification of said proteinaceous binding molecule. The purification tag enables the convenient purification of the proteinaceous binding molecule with monovalent binding properties against the target molecule.
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