发明公开
- 专利标题： BIOAVAILABLE COMBINATIONS FOR HCV TREATMENT
- 专利标题（中）： 有机组合，可用于治疗HCV治疗
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申请号： EP07821457.4申请日： 2007-10-17
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公开(公告)号： EP2081598A2公开(公告)日： 2009-07-29
- 发明人: VAN'T KLOOSTER, Gerben Albert Eleutherius , DE KOCK, Herman Augustinus , RABOISSON, Pierre Jean-Marie Bernard , VAN DEN EYNDE, Christel Florentina E.
- 申请人： Tibotec Pharmaceuticals Ltd.
- 申请人地址： Eastgate Village Eastgate Little Island Co Cork IE
- 专利权人： Tibotec Pharmaceuticals Ltd.
- 当前专利权人： Tibotec Pharmaceuticals Ltd.
- 当前专利权人地址： Eastgate Village Eastgate Little Island Co Cork IE
- 代理机构： Daelemans, Frank F.R.
- 优先权： EP06122446 20061017
- 国际公布： WO2008046860 20080424
- 主分类号： A61K45/06
- IPC分类号： A61K45/06 ; A61K38/04 ; A61K31/4709 ; A61K31/428 ; A61P31/12
摘要：
The present invention relates to the combination comprising an HCV NS3/4a protease inhibitor and a compound of formula (II). The combination is useful to improve the bioavailability of the HCV NS3/4a protease inhibitor. As such, the combination is useful for treating conditions associated with the Hepatitis C virus in patients. Pharmaceutical compositions and kits comprising this combination, and processes for preparing the combination and the pharmaceutical formulations are also provided.
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