发明公开
EP2087139A2 GENE EXPRESSION PROFILING BASED IDENTIFICATION OF GENOMIC SIGNATURES OF HIGH-RISK MULTIPLE MYELOMA AND USES THEREOF
有权
对基因表达的非常危险的多发性骨髓瘤的整形识别GIS的基因签名
- 专利标题： GENE EXPRESSION PROFILING BASED IDENTIFICATION OF GENOMIC SIGNATURES OF HIGH-RISK MULTIPLE MYELOMA AND USES THEREOF
- 专利标题（中）： 对基因表达的非常危险的多发性骨髓瘤的整形识别GIS的基因签名
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申请号： EP07861764.4申请日： 2007-11-07
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公开(公告)号： EP2087139A2公开(公告)日： 2009-08-12
- 发明人: SHAUGHNESSY, John D. , ZHAN, Fenghuang , BARLOGIE, Bart , BURLINGTON, Bart E.
- 申请人： The Board of Trustees of the University of Arkansas System
- 申请人地址： 2404 North University Avenue Little Rock, AR 72207-3608 US
- 专利权人： The Board of Trustees of the University of Arkansas System
- 当前专利权人： The Board of Trustees of the University of Arkansas System
- 当前专利权人地址： 2404 North University Avenue Little Rock, AR 72207-3608 US
- 代理机构： Heaton, Joanne Marie
- 优先权： US857456P 20061107
- 国际公布： WO2008057545 20080515
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/04
摘要：
The present invention discloses a method of gene expression profiling to identify genomic signatures linked to survival specific for a disease and a kit that can be used for performing such a method. Also disclosed herein is the use of such a method in classifying the disease into subsets, predicting clinical outcome and survival of an individual, selecting treatment for an individual suffering from a disease, predicting post-relapse risk and survival of an individual, correlating molecular classification of a disease with genomic signature defining the risk group or a combination thereof.
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