发明公开
- 专利标题： OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS
- 专利标题（中）： 优化的非规范锌指蛋白
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申请号： EP07853356.9申请日： 2007-12-13
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公开(公告)号： EP2092068A2公开(公告)日： 2009-08-26
- 发明人: CAI, Qihua C. , MILLER, Jeffrey , URNOV, Fyodor , SHUKLA, Vipula K. , PETOLINO, Joseph F. , BAKER, Lisa W. , GARRISON, Robbi J. , BLUE, Ryan C. , MITCHELL, Jon C. , ARNOLD, Nicole L. , WORDEN, Sarah E.
- 申请人： Dow AgroSciences LLC , Sangamo BioSciences, Inc.
- 申请人地址： 9330 Zionsville Road Indianapolis, IN 46268-1054 US
- 专利权人： Dow AgroSciences LLC,Sangamo BioSciences, Inc.
- 当前专利权人： Dow AgroSciences LLC,Sangamo BioSciences, Inc.
- 当前专利权人地址： 9330 Zionsville Road Indianapolis, IN 46268-1054 US
- 代理机构： Dey, Michael
- 优先权： US874911P 20061214; US932497P 20070530
- 国际公布： WO2008076290 20080626
- 主分类号： C12N15/62
- IPC分类号： C12N15/62 ; C07K14/00 ; C12N15/82 ; C12N15/09
摘要：
Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described
公开/授权文献
- EP2092068B1 Optimized non-canonical zinc finger proteins 公开/授权日：2014-10-08
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