发明授权
- 专利标题： PROCESS FOR PREPARING PRAVASTATIN
- 专利标题（中）： 用于生产普伐他汀
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申请号： EP07848031.6申请日： 2007-12-11
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公开(公告)号： EP2094841B1公开(公告)日： 2012-03-14
- 发明人: KLAASSEN, Paul , VOLLEBREGT, Adrianus Wilhelmus Hermanus , VAN DEN BERG, Marco Alexander , HANS, Marcus , VAN DER LAAN, Jan Metske
- 申请人： DSM Sinochem Pharmaceuticals Netherlands B.V.
- 申请人地址： Alexander Fleminglaan 1 2613 AX Delft NL
- 专利权人： DSM Sinochem Pharmaceuticals Netherlands B.V.
- 当前专利权人： DSM Sinochem Pharmaceuticals Netherlands B.V.
- 当前专利权人地址： Alexander Fleminglaan 1 2613 AX Delft NL
- 代理机构： De Vroom, Erik
- 优先权： EP06126046 20061213
- 国际公布： WO2008071673 20080619
- 主分类号： C12N9/02
- IPC分类号： C12N9/02 ; C12P7/62 ; C12P17/06
摘要：
The present invention provides a polypeptide having an amino acid sequence according to SEQ ID NO 3, SEQ ID NO 6 or SEQ ID NO 43-59. The present invention also provides a polynucleotide comprising a DNA sequence encoding these polypeptides and a method for isolating polynucleotides encoding polypeptides capable of improving the compactin into pravastatin conversion. Furthermore, the present invention provides a method for producing pravastatin and a pharmaceutical composition comprising pravastatin.
公开/授权文献
- EP2094841A1 PROCESS FOR PREPARING PRAVASTATIN 公开/授权日：2009-09-02
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