发明公开
EP2112880A2 ACYL BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
审中-公开
ACYLBIPIPERIDINYLVERBINDUNGEN,组成这样的化合物和治疗方法
- 专利标题: ACYL BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
- 专利标题(中): ACYLBIPIPERIDINYLVERBINDUNGEN,组成这样的化合物和治疗方法
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申请号: EP07862712.2申请日: 2007-12-10
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公开(公告)号: EP2112880A2公开(公告)日: 2009-11-04
- 发明人: WOOD, Harold B. , ADAMS, Alan D. , FREEMAN, Stanley , SZEWCZYK, Jason W. , SANTINI, Conrad , HUANG, Yong , MOSLEY, Ralph T.
- 申请人: Merck & Co., Inc.
- 申请人地址: 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构: Buchan, Gavin MacNicol
- 优先权: US874907P 20061214
- 国际公布: WO2008076243 20080626
- 主分类号: A01N43/40
- IPC分类号: A01N43/40 ; A61K31/445
摘要:
Bipiperidyl compounds of the formula: (I) are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.
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