发明公开
- 专利标题: FUSED AROMATIC PTP-1B INHIBITORS
- 专利标题(中): 稠合芳族PTP-18抑制剂
-
申请号: EP08706319.4申请日: 2008-01-24
-
公开(公告)号: EP2114971A1公开(公告)日: 2009-11-11
- 发明人: COLUCCI, John , WILSON, Marie-Claire , HAN, Yongxin , DUFRESNE, Claude , BELLEY, Michel , LAU, Cheuk, K. , BAYLY, Christopher
- 申请人: Merck Frosst Canada Ltd.
- 申请人地址: 16711 Trans-Canada Highway Kirkland, Québec H9H 3L1 CA
- 专利权人: Merck Frosst Canada Ltd.
- 当前专利权人: Merck Frosst Canada Ltd.
- 当前专利权人地址: 16711 Trans-Canada Highway Kirkland, Québec H9H 3L1 CA
- 代理机构: Buchan, Gavin MacNicol
- 优先权: US897700P 20070126
- 国际公布: WO2008089581 20080731
- 主分类号: C07F9/60
- IPC分类号: C07F9/60 ; A61K31/662 ; A61K31/675 ; A61P3/10 ; A61P35/00 ; C07F9/38 ; C07F9/40
摘要:
The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown (Formula I) above and methods of treating or preventing PTP-1B mediated diseases, including diabetes.
公开/授权文献
- EP2114971B1 FUSED AROMATIC PTP-1B INHIBITORS 公开/授权日:2015-06-17
信息查询