发明授权
- 专利标题： MACROCYCLIC COMPOUND
- 专利标题（中）： 大环化合物
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申请号： EP08721047.2申请日： 2008-02-29
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公开(公告)号： EP2119718B1公开(公告)日： 2012-04-11
- 发明人: SHIMMA, Nobuo , TSUKUDA, Takuo , KOYANO, Hiroshi , SUDA, Atsushi , HAYASE, Tadakatsu , HADA, Kihito , KAWASAKI, Ken-ichi , KOMIYAMA, Susumu , ONO, Naomi , YAMAZAKI, Toshikazu , SAITOH, Ryoichi , KOHCHI, Masami , HASEGAWA, Kiyoshi
- 申请人： Chugai Seiyaku Kabushiki Kaisha
- 申请人地址： 5-1 Ukima 5-chome Kita-ku Tokyo 115-8543 JP
- 专利权人： Chugai Seiyaku Kabushiki Kaisha
- 当前专利权人： Chugai Seiyaku Kabushiki Kaisha
- 当前专利权人地址： 5-1 Ukima 5-chome Kita-ku Tokyo 115-8543 JP
- 代理机构： Vossius & Partner
- 优先权： JP2007052072 20070301
- 国际公布： WO2008105526 20080904
- 主分类号： C07D497/08
- IPC分类号： C07D497/08 ; A61K31/529 ; A61K31/53 ; A61K31/5377 ; A61P1/16 ; A61P9/10 ; A61P11/00 ; A61P13/12 ; A61P17/00 ; A61P17/02 ; A61P19/02 ; A61P21/00 ; A61P25/00 ; A61P25/28 ; A61P29/00 ; A61P31/00 ; A61P35/00 ; A61P35/02 ; A61P37/02 ; A61P37/06
摘要：
Disclosed is a new class of compound which has HSP90 inhibitory activity and is useful as an antitumor agent or the like. Also disclosed is a compound which is useful as a synthesis intermediate for the compound having HSP90 inhibitory activity. Specifically disclosed is a compound represented by the general formula (1) below, or a pharmaceutically acceptable salt thereof. (In the formula, X, R1, R2, R3, R4, R5, R6, R7, L1, L2 and L3 are as defined in the description.)
公开/授权文献
- EP2119718A1 MACROCYCLIC COMPOUND 公开/授权日：2009-11-18
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