发明公开
- 专利标题： PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS
- 专利标题（中）： 一种用于β-内酰胺化合物的制备过程
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申请号： EP08717556.8申请日： 2008-03-10
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公开(公告)号： EP2121960A1公开(公告)日： 2009-11-25
- 发明人: DOES, VAN DER, Thomas , MOODY, Harold, Monro , DOOREN, VAN, Theodorus, Johannes, Godfried, Maria
- 申请人： DSM IP Assets B.V.
- 申请人地址： Het Overloon 1 6411 TE Heerlen NL
- 专利权人： DSM IP Assets B.V.
- 当前专利权人： DSM IP Assets B.V.
- 当前专利权人地址： Het Overloon 1 6411 TE Heerlen NL
- 代理机构： Misset, Onno
- 优先权： EP07103850 20070309
- 国际公布： WO2008110527 20080918
- 主分类号： C12P35/04
- IPC分类号： C12P35/04 ; C12P35/06 ; C12P37/04 ; C07C229/08
摘要：
The present invention describes a process for the synthesis of a semi-synthetic β-lactam compound from a nucleus and a side chain selected from the group consisting of D-phenylglycine and D-dihydro-phenylglycine in the form of a side chain ester and an enzyme catalyzing the coupling of the side chain ester to the nucleus characterized in that the side chain ester is not isolated as a solid intermediate.
公开/授权文献
- EP2121960B1 Process for the preparation of beta-lactam compounds 公开/授权日：2011-06-01
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