发明公开
- 专利标题： SOMATIC HYPERMUTATION SYSTEMS
- 专利标题（中）： SOMATIC超定系统
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申请号： EP08725985申请日： 2008-02-20
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公开(公告)号： EP2126105A4公开(公告)日： 2010-11-03
- 发明人: HORLICK ROBERT A , CUBITT ANDREW B , BOWERS PETER M
- 申请人： ANAPTYSBIO INC
- 专利权人： ANAPTYSBIO INC
- 当前专利权人： ANAPTYSBIO INC
- 优先权： US90241407 2007-02-20; US90462207 2007-03-01; US99597007 2007-09-28; US2012408 2008-01-09
- 主分类号： C12P19/34
- IPC分类号： C12P19/34 ; C12N15/11 ; C12N15/85
摘要：
This invention relates to methods for the generation of polynucleotide seed libraries and the use of these libraries in generating novel mutants of recombinant proteins and, more particularly, for generating focused libraries of recombinant human antibodies and screening for their affinity binding with target antigens.
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